Blood Flow Restriction Resistance Training in Tendon Rehabilitation
A scoping review on intervention parameters, physiological effects, and outcomes
DOI:
https://doi.org/10.51224/SRXIV.107Keywords:
Blood flow restriction; Tendinopathy; Resistance training; Exercise; Physiotherapy; TendonAbstract
Objective: To identify current evidence on blood flow restriction training (BFRT) in tendon injuries and healthy tendons, evaluating physiological tendon effects, intervention parameters and outcomes.
Methods: This scoping review was reported in accordance with the PRISMA Extension for Scoping Reviews (PRISMA-ScR). Databases searched included MEDLINE, CINAHL, AMED, EMBase, SPORTDiscus, Cochrane library (Controlled trials, Systematic reviews), and five trial registries. Two independent reviewers screened studies at title/abstract and full text. Following screening, data was extracted and charted, and presented as figures and tables alongside a narrative synthesis. Any study design conducted on adults, investigating the effects of BFRT on healthy tendons or tendon pathology were included. Data were extracted on physiological tendon effects, and intervention parameters and outcomes with BFRT.
Results: 13 studies were included, 3 on tendinopathy, 2 on tendon ruptures and 8 on healthy Achilles, patellar, supraspinatus and vastus lateralis tendons. A variety of outcomes were assessed, including pain, function, strength, and tendon morphological and mechanical properties, particularly changes in tendon thickness. BFRT intervention parameters were heterogeneously prescribed.
Conclusion: Despite a dearth of studies to date on the effects of BFRT on healthy tendons and in tendon pathologies, preliminary evidence for beneficial effects of BFRT on tendons and clinical outcomes is encouraging. As BFRT is a relatively novel method, definitive conclusions, and recommendations on BFRT in tendon rehabilitation cannot be made at present, which should be addressed in future research, due to the potential therapeutic benefits highlighted in this review.
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References
Dean, B. J. F., Dakin, S. G., Millar, N. L., & Carr, A. J. (2017). Review: Emerging concepts in the pathogenesis of tendinopathy. The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 15(6), 349-354.
Hopkins, C., Fu, S. C., Chua, E., Hu, X., Rolf, C., Mattila, V. M., et al. (2016). Critical review on the socio-economic impact of tendinopathy. Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology, 4, 9-20.
Magnusson, S. P., & Kjaer, M. (2019). The impact of loading, unloading, ageing and injury on the human tendon. The Journal of Physiology, 597(5), 1283-1298.
Millar, N. L., Silbernagel, K. G., Thorborg, K., Kirwan, P. D., Galatz, L. M., Abrams, G. D., et al. (2021). Tendinopathy. Nature Reviews.Disease Primers, 7(1), 1-020-00234-1.
Zwerver, J., Bredeweg, S. W., & van den Akker-Scheek, I. (2011). Prevalence of jumper's knee among nonelite athletes from different sports: A cross-sectional survey. The American Journal of Sports Medicine, 39(9), 1984-1988.
Canosa-Carro, L., Bravo-Aguilar, M., Abuin-Porras, V., Almazan-Polo, J., Garcia-Perez-de-Sevilla, G., Rodriguez-Costa, I., et al. (2022). Current understanding of the diagnosis and management of the tendinopathy: An update from the lab to the clinical practice. Disease-a-Month : DM, , 101314.
Skjong, C. C., Meininger, A. K., & Ho, S. S. (2012). Tendinopathy treatment: Where is the evidence? Clinics in Sports Medicine, 31(2), 329-350.
Lian, O. B., Engebretsen, L., & Bahr, R. (2005). Prevalence of jumper's knee among elite athletes from different sports: A cross-sectional study. The American Journal of Sports Medicine, 33(4), 561-567.
Holm, C., Kjaer, M., & Eliasson, P. (2015). Achilles tendon rupture--treatment and complications: A systematic review. Scandinavian Journal of Medicine & Science in Sports, 25(1), e1-10.
Nyyssonen, T., Luthje, P., & Kroger, H. (2008). The increasing incidence and difference in sex distribution of achilles tendon rupture in finland in 1987-1999. Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society, 97(3), 272-275.
Beyer, R., Kongsgaard, M., Hougs Kjaer, B., Ohlenschlaeger, T., Kjaer, M., & Magnusson, S. P. (2015). Heavy slow resistance versus eccentric training as treatment for achilles tendinopathy: A randomized controlled trial. The American Journal of Sports Medicine, 43(7), 1704-1711.
Kongsgaard, M., Qvortrup, K., Larsen, J., Aagaard, P., Doessing, S., Hansen, P., et al. (2010). Fibril morphology and tendon mechanical properties in patellar tendinopathy: Effects of heavy slow resistance training. The American Journal of Sports Medicine, 38(4), 749-756.
Christensen, M., Zellers, J. A., Kjaer, I. L., Silbernagel, K. G., & Rathleff, M. S. (2020). Resistance exercises in early functional rehabilitation for achilles tendon ruptures are poorly described: A scoping review. The Journal of Orthopaedic and Sports Physical Therapy, 50(12), 681-690.
Bohm, S., Mersmann, F., & Arampatzis, A. (2015). Human tendon adaptation in response to mechanical loading: A systematic review and meta-analysis of exercise intervention studies on healthy adults. Sports Medicine - Open, 1(1), 7-015-0009-9. Epub 2015 Mar 27.
Couppe, C., Svensson, R. B., Silbernagel, K. G., Langberg, H., & Magnusson, S. P. (2015). Eccentric or concentric exercises for the treatment of tendinopathies? The Journal of Orthopaedic and Sports Physical Therapy, 45(11), 853-863.
Loenneke, J. P., Abe, T., Wilson, J. M., Ugrinowitsch, C., & Bemben, M. G. (2012). Blood flow restriction: How does it work? Frontiers in Physiology, 3, 392.
Lorenz, D. S., Bailey, L., Wilk, K. E., Mangine, R. E., Head, P., Grindstaff, T. L., et al. (2021). Blood flow restriction training. Journal of Athletic Training, 56(9), 937-944.
Barber-Westin, S., & Noyes, F. R. (2019). Blood flow-restricted training for lower extremity muscle weakness due to knee pathology: A systematic review. Sports Health, 11(1), 69-83.
Hughes, L., Paton, B., Rosenblatt, B., Gissane, C., & Patterson, S. D. (2017). Blood flow restriction training in clinical musculoskeletal rehabilitation: A systematic review and meta-analysis. British Journal of Sports Medicine, 51(13), 1003-1011.
Nitzsche, N., Stauber, A., Tiede, S., & Schulz, H. (2021). The effectiveness of blood-flow restricted resistance training in the musculoskeletal rehabilitation of patients with lower limb disorders: A systematic review and meta-analysis. Clinical Rehabilitation, 35(9), 1221-1234.
Hughes, L., Paton, B., Haddad, F., Rosenblatt, B., Gissane, C., & Patterson, S. D. (2018). Comparison of the acute perceptual and blood pressure response to heavy load and light load blood flow restriction resistance exercise in anterior cruciate ligament reconstruction patients and non-injured populations. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 33, 54-61.
Caetano, D., Oliveira, C., Correia, C., Barbosa, P., Montes, A., & Carvalho, P. (2021). Rehabilitation outcomes and parameters of blood flow restriction training in ACL injury: A scoping review. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 49, 129-137.
Miller, B. C., Tirko, A. W., Shipe, J. M., Sumeriski, O. R., & Moran, K. (2021). The systemic effects of blood flow restriction training: A systematic review. International Journal of Sports Physical Therapy, 16(4), 978-990.
Karabulut, M., Esparza, B., Dowllah, I. M., & Karabulut, U. (2021). The impact of low-intensity blood flow restriction endurance training on aerobic capacity, hemodynamics, and arterial stiffness. The Journal of Sports Medicine and Physical Fitness, 61(7), 877-884.
Karabulut, M., Sherk, V. D., Bemben, D. A., & Bemben, M. G. (2013). Inflammation marker, damage marker and anabolic hormone responses to resistance training with vascular restriction in older males. Clinical Physiology and Functional Imaging, 33(5), 393-399.
Neto, G. R., Sousa, M. S., Costa e Silva, G. V., Gil, A. L., Salles, B. F., & Novaes, J. S. (2016). Acute resistance exercise with blood flow restriction effects on heart rate, double product, oxygen saturation and perceived exertion. Clinical Physiology and Functional Imaging, 36(1), 53-59.
da Silva, J. C. G., Silva, K. F., Domingos-Gomes, J. R., Batista, G. R., da Silva Freitas, E. D., Torres, V. B. C., et al. (2019). Aerobic exercise with blood flow restriction affects mood state in a similar fashion to high intensity interval exercise. Physiology & Behavior, 211, 112677.
Silva, J. C. G., Aniceto, R. R., Oliota-Ribeiro, L. S., Neto, G. R., Leandro, L. S., & Cirilo-Sousa, M. S. (2018). Mood effects of blood flow restriction resistance exercise among basketball players. Perceptual and Motor Skills, 125(4), 788-801.
Okita, K., Takada, S., Morita, N., Takahashi, M., Hirabayashi, K., Yokota, T., et al. (2019). Resistance training with interval blood flow restriction effectively enhances intramuscular metabolic stress with less ischemic duration and discomfort. Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme, 44(7), 759-764.
Bowman, E. N., Elshaar, R., Milligan, H., Jue, G., Mohr, K., Brown, P., et al. (2019). Proximal, distal, and contralateral effects of blood flow restriction training on the lower extremities: A randomized controlled trial. Sports Health, 11(2), 149-156.
Freitas, E. D. S., Karabulut, M., & Bemben, M. G. (2021). The evolution of blood flow restricted exercise. Frontiers in Physiology, 12, 747759.
Krzysztofik, M., Wilk, M., Wojdala, G., & Golas, A. (2019). Maximizing muscle hypertrophy: A systematic review of advanced resistance training techniques and methods. International Journal of Environmental Research and Public Health, 16(24), 10.3390/ijerph16244897.
Kataoka, R., Vasenina, E., Hammert, W. B., Ibrahim, A. H., Dankel, S. J., & Buckner, S. L. (2022). Muscle growth adaptations to high-load training and low-load training with blood flow restriction in calf muscles. European Journal of Applied Physiology,
Centner, C., Wiegel, P., Gollhofer, A., & Konig, D. (2019). Effects of blood flow restriction training on muscular strength and hypertrophy in older individuals: A systematic review and meta-analysis. Sports Medicine (Auckland, N.Z.), 49(1), 95-108.
Shiromaru, F. F., de Salles Painelli, V., Silva-Batista, C., Longo, A. R., Lasevicius, T., Schoenfeld, B. J., et al. (2019). Differential muscle hypertrophy and edema responses between high-load and low-load exercise with blood flow restriction. Scandinavian Journal of Medicine & Science in Sports, 29(11), 1713-1726.
Ohta, H., Kurosawa, H., Ikeda, H., Iwase, Y., Satou, N., & Nakamura, S. (2003). Low-load resistance muscular training with moderate restriction of blood flow after anterior cruciate ligament reconstruction. Acta Orthopaedica Scandinavica, 74(1), 62-68.
Bryk, F. F., Dos Reis, A. C., Fingerhut, D., Araujo, T., Schutzer, M., Cury Rde, P., et al. (2016). Exercises with partial vascular occlusion in patients with knee osteoarthritis: A randomized clinical trial. Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA, 24(5), 1580-1586.
Giles, L., Webster, K. E., McClelland, J., & Cook, J. L. (2017). Quadriceps strengthening with and without blood flow restriction in the treatment of patellofemoral pain: A double-blind randomised trial. British Journal of Sports Medicine, 51(23), 1688-1694.
Ferraz, R. B., Gualano, B., Rodrigues, R., Kurimori, C. O., Fuller, R., Lima, F. R., et al. (2018). Benefits of resistance training with blood flow restriction in knee osteoarthritis. Medicine and Science in Sports and Exercise, 50(5), 897-905.
Grantham, B., Korakakis, V., & O'Sullivan, K. (2021). Does blood flow restriction training enhance clinical outcomes in knee osteoarthritis: A systematic review and meta-analysis. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 49, 37-49.
Korakakis, V., Whiteley, R., & Giakas, G. (2018). Low load resistance training with blood flow restriction decreases anterior knee pain more than resistance training alone. A pilot randomised controlled trial. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 34, 121-128.
Ferlito, J. V., Pecce, S. A. P., Oselame, L., & De Marchi, T. (2020). The blood flow restriction training effect in knee osteoarthritis people: A systematic review and meta-analysis. Clinical Rehabilitation, 34(11), 1378-1390.
Korakakis, V., Whiteley, R., & Epameinontidis, K. (2018). Blood flow restriction induces hypoalgesia in recreationally active adult male anterior knee pain patients allowing therapeutic exercise loading. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 32, 235-243.
Hughes, L., Grant, I., & Patterson, S. D. (2021). Aerobic exercise with blood flow restriction causes local and systemic hypoalgesia and increases circulating opioid and endocannabinoid levels. Journal of Applied Physiology (Bethesda, Md.: 1985), 131(5), 1460-1468.
Hughes, L., & Patterson, S. D. (2019). Low intensity blood flow restriction exercise: Rationale for a hypoalgesia effect. Medical Hypotheses, 132, 109370.
Hughes, L., & Patterson, S. D. (2020). The effect of blood flow restriction exercise on exercise-induced hypoalgesia and endogenous opioid and endocannabinoid mechanisms of pain modulation. Journal of Applied Physiology (Bethesda, Md.: 1985), 128(4), 914-924.
Loenneke, J. P., Fahs, C. A., Rossow, L. M., Abe, T., & Bemben, M. G. (2012). The anabolic benefits of venous blood flow restriction training may be induced by muscle cell swelling. Medical Hypotheses, 78(1), 151-154.
Lixandrao, M. E., Ugrinowitsch, C., Berton, R., Vechin, F. C., Conceicao, M. S., Damas, F., et al. (2018). Magnitude of muscle strength and mass adaptations between high-load resistance training versus low-load resistance training associated with blood-flow restriction: A systematic review and meta-analysis. Sports Medicine (Auckland, N.Z.), 48(2), 361-378.
Manini, T. M., & Clark, B. C. (2009). Blood flow restricted exercise and skeletal muscle health. Exercise and Sport Sciences Reviews, 37(2), 78-85.
Hughes, L., Patterson, S. D., Haddad, F., Rosenblatt, B., Gissane, C., McCarthy, D., et al. (2019). Examination of the comfort and pain experienced with blood flow restriction training during post-surgery rehabilitation of anterior cruciate ligament reconstruction patients: A UK national health service trial. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 39, 90-98.
Abe, T., Loenneke, J. P., Fahs, C. A., Rossow, L. M., Thiebaud, R. S., & Bemben, M. G. (2012). Exercise intensity and muscle hypertrophy in blood flow-restricted limbs and non-restricted muscles: A brief review. Clinical Physiology and Functional Imaging, 32(4), 247-252.
Yasuda, T., Loenneke, J. P., Thiebaud, R. S., & Abe, T. (2012). Effects of blood flow restricted low-intensity concentric or eccentric training on muscle size and strength. PloS One, 7(12), e52843.
Martin-Hernandez, J., Marin, P. J., Menendez, H., Ferrero, C., Loenneke, J. P., & Herrero, A. J. (2013). Muscular adaptations after two different volumes of blood flow-restricted training. Scandinavian Journal of Medicine & Science in Sports, 23(2), e114-20.
Loenneke, J. P., Wilson, J. M., Balapur, A., Thrower, A. D., Barnes, J. T., & Pujol, T. J. (2012). Time under tension decreased with blood flow-restricted exercise. Clinical Physiology and Functional Imaging, 32(4), 268-273.
Pearson, S. J., & Hussain, S. R. (2015). A review on the mechanisms of blood-flow restriction resistance training-induced muscle hypertrophy. Sports Medicine (Auckland, N.Z.), 45(2), 187-200.
Rossi, F. E., de Freitas, M. C., Zanchi, N. E., Lira, F. S., & Cholewa, J. M. (2018). The role of inflammation and immune cells in blood flow restriction training adaptation: A review. Frontiers in Physiology, 9, 1376.
Klein, M. B., Pham, H., Yalamanchi, N., & Chang, J. (2001). Flexor tendon wound healing in vitro: The effect of lactate on tendon cell proliferation and collagen production. The Journal of Hand Surgery, 26(5), 847-854.
Boesen, A. P., Dideriksen, K., Couppe, C., Magnusson, S. P., Schjerling, P., Boesen, M., et al. (2013). Tendon and skeletal muscle matrix gene expression and functional responses to immobilisation and rehabilitation in young males: Effect of growth hormone administration. The Journal of Physiology, 591(23), 6039-6052.
Tricco, A. C., Lillie, E., Zarin, W., O'Brien, K. K., Colquhoun, H., Levac, D., et al. (2018). PRISMA extension for scoping reviews (PRISMA-ScR): Checklist and explanation. Annals of Internal Medicine, 169(7), 467-473.
Skovlund SV, Aagaard P, Larsen P, Svensson RB, Kjaer M, Magnusson SP. The effect of low‐load resistance training with blood flow restriction on chronic patellar tendinopathy — A case series. Translational Sports Medicine, 2020;3.
Sata S. Kaatsu training for patella tendinitis patient. Int J KAATSU Train Res. 2005;1(1), 29-32.
Cuddeford, T., & Brumitt, J. (2020). In-season rehabilitation program using blood flow restriction therapy for two decathletes with patellar tendinopathy: A case report. International Journal of Sports Physical Therapy, 15(6), 1184-1195.
Wentzell, M. (2018). Post-operative rehabilitation of a distal biceps brachii tendon reattachment in a weightlifter: A case report. The Journal of the Canadian Chiropractic Association, 62(3), 193-201.
Yow, B. G., Tennent, D. J., Dowd, T. C., Loenneke, J. P., & Owens, J. G. (2018). Blood flow restriction training after achilles tendon rupture. The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons, 57(3), 635-638.
Centner, C., Lauber, B., Seynnes, O. R., Jerger, S., Sohnius, T., Gollhofer, A., et al. (2019). Low-load blood flow restriction training induces similar morphological and mechanical achilles tendon adaptations compared with high-load resistance training. Journal of Applied Physiology (Bethesda, Md.: 1985), 127(6), 1660-1667.
Chulvi-Medrano, I., Picon-Martinez, M., Cortell-Tormo, J. M., Tortosa-Martinez, J., Alonso-Aubin, D. A., & Alakhdar, Y. (2020). Different time course of recovery in achilles tendon thickness after low-load resistance training with and without blood flow restriction. Journal of Sport Rehabilitation, 30(2), 300-305.
Picon-Martinez, M., Chulvi-Medrano, I., Cortell-Tormo, J. M., Alonso-Aubin, D. A., Alakhdar, Y., & Laurentino, G. (2021). Acute effects of resistance training with blood flow restriction on achilles tendon thickness. Journal of Human Kinetics, 78, 101-109.
Gavanda, S., Isenmann, E., Schloder, Y., Roth, R., Freiwald, J., Schiffer, T., et al. (2020). Low-intensity blood flow restriction calf muscle training leads to similar functional and structural adaptations than conventional low-load strength training: A randomized controlled trial. PloS One, 15(6), e0235377.
Canfer, R. J., Chaudry, S., & Miller, S. C. (2021). Thermographic assessment of the immediate and short term-effects of blood flow restriction exercise on achilles tendon skin temperature. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 49, 171-177.
Centner, C., Jerger, S., Lauber, B., Seynnes, O., Friedrich, T., Lolli, D., et al. (2021). Low-load blood flow restriction and high-load resistance training induce comparable changes in patellar tendon properties. Medicine and Science in Sports and Exercise,
Brumitt, J., Hutchison, M. K., Kang, D., Klemmer, Z., Stroud, M., Cheng, E., et al. (2020). Blood flow restriction training for the rotator cuff: A randomized controlled trial. International Journal of Sports Physiology and Performance, , 1-6.
Kubo, K., Komuro, T., Ishiguro, N., Tsunoda, N., Sato, Y., Ishii, N., et al. (2006). Effects of low-load resistance training with vascular occlusion on the mechanical properties of muscle and tendon. Journal of Applied Biomechanics, 22(2), 112-119.
Burton, I., & McCormack, A. (2021). The implementation of resistance training principles in exercise interventions for lower limb tendinopathy: A systematic review. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 50, 97-113.
Palmieri-Smith, R. M., & Lepley, L. K. (2015). Quadriceps strength asymmetry after anterior cruciate ligament reconstruction alters knee joint biomechanics and functional performance at time of return to activity. The American Journal of Sports Medicine, 43(7), 1662-1669.
Ladlow, P., Coppack, R. J., Dharm-Datta, S., Conway, D., Sellon, E., Patterson, S. D., et al. (2018). Low-load resistance training with blood flow restriction improves clinical outcomes in musculoskeletal rehabilitation: A single-blind randomized controlled trial. Frontiers in Physiology, 9, 1269.
Patterson, S. D., Hughes, L., Warmington, S., Burr, J., Scott, B. R., Owens, J., et al. (2019). Blood flow restriction exercise: Considerations of methodology, application, and safety. Frontiers in Physiology, 10, 533.
Constantinou, A., Mamais, I., Papathanasiou, G., Lamnisos, D., & Stasinopoulos, D. (2022). Comparing hip and knee focused exercises versus hip and knee focused exercises with the use of blood flow restriction training in adults with patellofemoral pain: A randomized controlled trial. European Journal of Physical and Rehabilitation Medicine,
Rodrigues, R., Ferraz, R. B., Kurimori, C. O., Guedes, L. K., Lima, F. R., de Sa-Pinto, A. L., et al. (2020). Low-load resistance training with blood-flow restriction in relation to muscle function, mass, and functionality in women with rheumatoid arthritis. Arthritis Care & Research, 72(6), 787-797.
Larsen, P., Platzer, O. J., Lollesgaard, L., Pedersen, S. K., Nielsen, P. K., Rathleff, M. S., et al. (2021). Blood-flow restricted exercise following ankle fractures - A feasibility study. Foot and Ankle Surgery : Official Journal of the European Society of Foot and Ankle Surgeons,
Kilgas, M. A., Lytle, L. L. M., Drum, S. N., & Elmer, S. J. (2019). Exercise with blood flow restriction to improve quadriceps function long after ACL reconstruction. International Journal of Sports Medicine, 40(10), 650-656.
Kraemer, W. J., & Ratamess, N. A. (2004). Fundamentals of resistance training: Progression and exercise prescription. Medicine and Science in Sports and Exercise, 36(4), 674-688.
Schoenfeld, B. J., Contreras, B., Krieger, J., Grgic, J., Delcastillo, K., Belliard, R., et al. (2019). Resistance training volume enhances muscle hypertrophy but not strength in trained men. Medicine and Science in Sports and Exercise, 51(1), 94-103.
Schoenfeld, B. J., Grgic, J., Ogborn, D., & Krieger, J. W. (2017). Strength and hypertrophy adaptations between low- vs. high-load resistance training: A systematic review and meta-analysis. Journal of Strength and Conditioning Research, 31(12), 3508-3523.
Lasevicius, T., Schoenfeld, B. J., Silva-Batista, C., Barros, T. S., Aihara, A. Y., Brendon, H., et al. (2019). Muscle failure promotes greater muscle hypertrophy in low-load but not in high-load resistance training. Journal of Strength and Conditioning Research,
Lasevicius, T., Ugrinowitsch, C., Schoenfeld, B. J., Roschel, H., Tavares, L. D., De Souza, E. O., et al. (2018). Effects of different intensities of resistance training with equated volume load on muscle strength and hypertrophy. European Journal of Sport Science, 18(6), 772-780.
Yasuda, T., Loenneke, J. P., Ogasawara, R., & Abe, T. (2013). Influence of continuous or intermittent blood flow restriction on muscle activation during low-intensity multiple sets of resistance exercise. Acta Physiologica Hungarica, 100(4), 419-426.
Loenneke, J. P., Kearney, M. L., Thrower, A. D., Collins, S., & Pujol, T. J. (2010). The acute response of practical occlusion in the knee extensors. Journal of Strength and Conditioning Research, 24(10), 2831-2834.
Loenneke, J. P., Wilson, G. J., & Wilson, J. M. (2010). A mechanistic approach to blood flow occlusion. International Journal of Sports Medicine, 31(1), 1-4.
Loenneke, J. P., Balapur, A., Thrower, A. D., Barnes, J. T., & Pujol, T. J. (2011). The perceptual responses to occluded exercise. International Journal of Sports Medicine, 32(3), 181-184.
Mattocks, K. T., Jessee, M. B., Counts, B. R., Buckner, S. L., Grant Mouser, J., Dankel, S. J., et al. (2017). The effects of upper body exercise across different levels of blood flow restriction on arterial occlusion pressure and perceptual responses. Physiology & Behavior, 171, 181-186.
Jessee, M. B., Buckner, S. L., Dankel, S. J., Counts, B. R., Abe, T., & Loenneke, J. P. (2016). The influence of cuff width, sex, and race on arterial occlusion: Implications for blood flow restriction research. Sports Medicine (Auckland, N.Z.), 46(6), 913-921.
Martin-Hernandez, J., Ruiz-Aguado, J., Herrero, A. J., Loenneke, J. P., Aagaard, P., Cristi-Montero, C., et al. (2017). Adaptation of perceptual responses to low-load blood flow restriction training. Journal of Strength and Conditioning Research, 31(3), 765-772.
Loenneke, J. P., Balapur, A., Thrower, A. D., Barnes, J. T., & Pujol, T. J. (2011). The perceptual responses to occluded exercise. International Journal of Sports Medicine, 32(3), 181-184.
Freitas, E. D. S., Miller, R. M., Heishman, A. D., Aniceto, R. R., Larson, R., Pereira, H. M., et al. (2021). The perceptual responses of individuals with multiple sclerosis to blood flow restriction versus traditional resistance exercise. Physiology & Behavior, 229, 113219.
Suga, T., Dora, K., Mok, E., Sugimoto, T., Tomoo, K., Takada, S., et al. (2021). Exercise adherence-related perceptual responses to low-load blood flow restriction resistance exercise in young adults: A pilot study. Physiological Reports, 9(23), e15122.
Lambert, B., Hedt, C., Daum, J., Taft, C., Chaliki, K., Epner, E., et al. (2021). Blood flow restriction training for the shoulder: A case for proximal benefit. The American Journal of Sports Medicine, 49(10), 2716-2728.
Yasuda, T., Fujita, S., Ogasawara, R., Sato, Y., & Abe, T. (2010). Effects of low-intensity bench press training with restricted arm muscle blood flow on chest muscle hypertrophy: A pilot study. Clinical Physiology and Functional Imaging, 30(5), 338-343.
Abe, T., Fujita, S., Nakajima, T., Sakamaki, M., Ozaki, H., Ogasawara, R., et al. (2010). Effects of low-intensity cycle training with restricted leg blood flow on thigh muscle volume and VO2MAX in young men. Journal of Sports Science & Medicine, 9(3), 452-458.
Abe, T., Sakamaki, M., Fujita, S., Ozaki, H., Sugaya, M., Sato, Y., et al. (2010). Effects of low-intensity walk training with restricted leg blood flow on muscle strength and aerobic capacity in older adults. Journal of Geriatric Physical Therapy (2001), 33(1), 34-40.
Centner, C., Zdzieblik, D., Roberts, L., Gollhofer, A., & Konig, D. (2019). Effects of blood flow restriction training with protein supplementation on muscle mass and strength in older men. Journal of Sports Science & Medicine, 18(3), 471-478.
Takarada, Y., Sato, Y., & Ishii, N. (2002). Effects of resistance exercise combined with vascular occlusion on muscle function in athletes. European Journal of Applied Physiology, 86(4), 308-314.
Madarame, H., Neya, M., Ochi, E., Nakazato, K., Sato, Y., & Ishii, N. (2008). Cross-transfer effects of resistance training with blood flow restriction. Medicine and Science in Sports and Exercise, 40(2), 258-263.
Curran, M. T., Bedi, A., Mendias, C. L., Wojtys, E. M., Kujawa, M. V., & Palmieri-Smith, R. M. (2020). Blood flow restriction training applied with high-intensity exercise does not improve quadriceps muscle function after anterior cruciate ligament reconstruction: A randomized controlled trial. The American Journal of Sports Medicine, 48(4), 825-837.
Gronfeldt, B. M., Lindberg Nielsen, J., Mieritz, R. M., Lund, H., & Aagaard, P. (2020). Effect of blood-flow restricted vs heavy-load strength training on muscle strength: Systematic review and meta-analysis. Scandinavian Journal of Medicine & Science in Sports, 30(5), 837-848.
Hill, E. C., Housh, T. J., Keller, J. L., Smith, C. M., Anders, J. V., Schmidt, R. J., et al. (2020). Low-load blood flow restriction elicits greater concentric strength than non-blood flow restriction resistance training but similar isometric strength and muscle size. European Journal of Applied Physiology, 120(2), 425-441.
Lixandrao, M. E., Ugrinowitsch, C., Laurentino, G., Libardi, C. A., Aihara, A. Y., Cardoso, F. N., et al. (2015). Effects of exercise intensity and occlusion pressure after 12 weeks of resistance training with blood-flow restriction. European Journal of Applied Physiology, 115(12), 2471-2480.
Vechin, F. C., Libardi, C. A., Conceicao, M. S., Damas, F. R., Lixandrao, M. E., Berton, R. P., et al. (2015). Comparisons between low-intensity resistance training with blood flow restriction and high-intensity resistance training on quadriceps muscle mass and strength in elderly. Journal of Strength and Conditioning Research, 29(4), 1071-1076.
Hughes, L., Rosenblatt, B., Haddad, F., Gissane, C., McCarthy, D., Clarke, T., et al. (2019). Comparing the effectiveness of blood flow restriction and traditional heavy load resistance training in the post-surgery rehabilitation of anterior cruciate ligament reconstruction patients: A UK national health service randomised controlled trial. Sports Medicine (Auckland, N.Z.), 49(11), 1787-1805.
Loenneke, J. P., Young, K. C., Wilson, J. M., & Andersen, J. C. (2013). Rehabilitation of an osteochondral fracture using blood flow restricted exercise: A case review. Journal of Bodywork and Movement Therapies, 17(1), 42-45.
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